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In 10 Minutes, I’ll Give You The Truth About Suhagra

Posted On December 17, 2024 at 10:31 am by / Comments Off on In 10 Minutes, I’ll Give You The Truth About Suhagra

Efficacy and Safety of Tadalafil 5 mg Administered Once Daily in Korean Men with Erectile Dysfunction: A Prospective, Multicenter Study

As a result, countless ladies have yelled “Oh yes. In healthy male volunteers, there was no evidence of a clinically significant effect of azithromycin 500 mg daily for 3 days on the systemic exposure of sildenafil or its major circulating metabolite. Yohimbine has been shown in some studies to improve erectile function in men with erectile dysfunction. NEW CLOUD NINE straightenersSHOP NOW. People with both ED and BPH took the survey after 4 weeks. RasH2 mice when administered at the maximum possible doses of 100 mg/kg for 6 months and 200 mg/kg for 4 months. Viagra is available in three strengths: 25 milligrams mg, 50 mg, and 100 mg. It is usually taken with or without food one hour before sexual activity. OTC ED pills are supplements. 6 mg/kg, or placebo daily. Keep these considerations in mind if your doctor prescribes sildenafil for you. More than 3,000 men participated in clinical trials of tadalafil.

Attention-grabbing Ways To Suhagra

Efficacy of dapoxetine treatment in Chinese patients with premature ejaculation and possible factors affecting efficacy in the real world practice

They are the same medicine. In February 2007, it was announced that Boots, the UK pharmacy chain, would try over the counter sales of Viagra https://farmacia-protetta.it/acquista-suhagra-25mg-50mg-100mg/ in stores in Manchester, England. Zanotti says there are a few drugs that may help increase your interest in sex. Cialis comes as oral tablets that are available in three strengths: 5 milligrams mg, 10 mg, and 20 mg. Compared with placebo, a greater improvement on all the evaluated end points was reported. The study showed that more people who took Cialis were able to pass their stones than people who took tamsulosin. NHS New Medicine Service. The Food and Drug Administration FDA has approved Cialis for use in adults to treat ED, BPH, and ED and BPH symptoms together. Viagra 100mg is the highest dose of Viagra available. Sildenafil is the active ingredient in Viagra and the generic version. Especially tell your healthcare provider if you take any of the following. A full list of the most frequent side effects can be found in the manufacturer’s patient information leaflet supplied with tablets links below. Tadalafil is >9,000 fold more potent for PDE5 than for PDE8, PDE9,and PDE10. The use of VIAGRA offers no protection against sexually transmitted diseases. The speaker and Public Health consultant participated in discussions but did not rate the risks and benefits. Tip I will suggest you to take a shower with warm water or just wash your face, forearms,legs wi. You should not take more than one PDE 5 inhibitor medicine. For benign prostatic hyperplasia, tadalafil relaxes the muscles of the bladder and prostate, making it easier to urinate and reducing symptoms. Although betel nut may boost libido, it’s not recommended for anyone because it is highly addictive. There are many reasons why a female could have no sex drive, ranging from relationship problems to stress or physical health conditions. Visit female hair removal.

The Secret Of Suhagra

Sildenafil

This means that the price for alprostadil will be higher when compared with generic alternatives to other ED medications. ErrorEmail field is required. Cochrane Database Syst Rev. If you have your own private paper prescription please post to our pharmacy details. Here’s how to get the maximum effect from as needed or. The manufacturer’s advice is that Cialis tablets are not suitable to be split, and patients should use the minimum effective dose as a whole tablet. The symptoms included urinary urgency sudden need to urinate, weak urine stream, and straining to urinate. This study was designed to evaluate the effect of single doses of 5 mg vardenafil stage 1 and 10 mg vardenafil stage 2 compared to placebo, when administered to a single cohort of BPH patients n=24 on stable therapy with alfuzosin 10 mg daily for at least four weeks. Call your doctor right away if you have blurred vision, confusion, dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly, sweating, or unusual tiredness or weakness. Do not use this medicine if you are also using a nitrate medicine for angina or high blood pressure. Patients with cardiovascular issues should exercise caution. Not being able to perform can damage your self esteem and lead to strain in your romantic relationships. Learn about what foods to eat or avoid for erectile dysfunction here. Discuss your health with your doctor to ensure that you are healthy enough for sex. “Before it was even approved, we were pleased that the little pink pill was sparking more conversations about women’s sexual dysfunction,” said Dr.

Precautions

Then they’ll adjust it over time to reach the amount that’s right for you. Typically taken 30 to 60 minutes before sexual activity, its effects can last up to four hours. Viagra is approved to treat erectile dysfunction ED in males ages 18 years and older. To learn more about Viagra, see these articles. Electrical health and diagnostics. VIAGRA does not protect against sexually transmitted diseases, including HIV. It starts working to improve erectile function as soon as 30 minutes after you take your dose. We break down seven of the best ED medications and everything you need to know about them. Your gift can go 3X as far to shape the future of healthcare. Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder: a double blind, placebo controlled study. Sildenafil oral liquid should be stored at room temperature below 86 F 30 C or in the refrigerator, between 36 F to 46 F 2 C to 8 C. We are extremely proud of our members’ significant contributions to patient health, from diligent skin cancer screening to applying the most appropriate medical and/or surgical interventions, including Mohs micrographic surgery. A total of 17 patients entered Study I. Just like your local GP, we’re here to support you with expert, confidential advice and treatment but without the travel and waiting time. Only three risks scored above 1, the potential drug drug interaction with riociguat which scored 2. There aren’t any known ways to permanently increase the size of a penis. To use the oral liquid. Visit audio and visual tech. Consent, Privacy and Legal. However, after you take your nightly dose, you should refrain from drinking alcohol until the next morning. Golombek of Universidad Nacional de Quilmes, Argentina, for their discovery that sildenafil helps treat jet lag recovery in hamsters. All the men had from moderate to severe premature ejaculation – on average, the men were ejaculating within one minute of penetration. This “molecular chaperone” can help support hormone signaling pathways such as those for estrogen and testosterone. For more information visit Dose Pharmacy. Sudden severe loss of vision see below for more information. Hydroquinone and Tretinoin. Cole’s regular column on health and wellness in Outside Magazine. Generic tadalafil is available at much lower cost, from 40p per tablet.

Storage

However, sexual stimulation is still needed. How do pills for erectile dysfunction work. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors. Always discuss with your doctor first to see if Cialis is a suitable treatment for you. Men’s value packs and bundles. Cialis Together has recently been re classified as a pharmacy medication. எனவே, அதை மாற்றீடாக பயன்படுத்தலாம். According to a 2013 study, around 22% of women under 20 experienced FSD, while a significant 75% of those aged 40 50 suffered from sexual dysfunction. D = do not know; Shaded boxes = consensus reached. The change isn’t permanent, though.

What are the brand names for vardenafil?

These relax your blood vessels in the same way as PDE 5 inhibitors in ED tablets do. The Boots guide to the best hair dryers. A small 2021 study involving 52 people found that a combination of ginseng and vitamin E may help improve ED, especially when compared with a placebo. There have been studies done which found that it is also safe and effective in postmenopausal women, but currently there is not enough evidence to license the use of Flibanserin in these women. Please see Full Prescribing Information and Patient Information. Permanent damage to the penis may occur if priapism is not treated quickly. If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. When using Tadapox 80mg, it is important to observe the following precautions. Here are some questions you might want to ask. Research studies sometimes don’t use the terminology in this way. There have been rare reports of prolonged erections greater than 4 hours and priapism painful erections greater than 6 hours in duration for this class of compounds, including vardenafil. Most people find that they’re effective at producing an erection. For example, more blood flow to the face can cause a flushed face. In the US Call your doctor for medical advice about side effects. If you take more tadalafil than you’ve been prescribed, speak to your doctor straight away. Sex and gender exist on spectrums. View Pharmacy Profile. Such countries are known to have equally advanced pharmaceutical and pharmacy regulatory systems. These may be the best approach to treating the condition since there are no safe and effective alternative treatments for ED. In controlled studies, Sildenafil 50mg was found to be effective in 74% of men with erectile dysfunction. Baby and child health. Mayo Clinic does not endorse companies or products. Finasteride is a first line treatment the first treatment used when medications are recommended for BPH. Do not use LEVITRA in patients on renal dialysis. Cole’s regular column on health and wellness in Outside Magazine.

Quizzes

Cialis doesn’t increase the size of a penis. Tadalafil offers the same treatment at a cheaper price. Use of the term “male” in this article refers to sex assigned at birth. 2 in patients taking placebo. The standard daily dose is 5mg. Women who are pregnant or breastfeeding should not use either drug. About Viagra 50 mg Tablet. It may be a combination of sexual performance and sexual desire. Web Policies FOIA HHS Vulnerability Disclosure. This means their ED symptoms eased while they were taking Cialis. For effective and appropriate treatment, speak with a doctor. Fast service and quickly shipping also apprec. Most ED pills take about 15–45 minutes on average to work. Levitra is not designed for daily use. In addition, the majority of men who took dapoxetine discontinued treatment. Do not mix the liquid with other medications or add anything to flavor the medication. 866 294 3772 More questions. You can report side effects to the FDA at or by calling 800 FDA 1088. Stop taking vardenafil and get help right away if you have any of the following symptoms of a serious allergic reaction. The maximum dose of Viagra is 100 mg. FDA encourages anyone aware of a serious side effect, including consumers or patients, to make a MedWatch report. Medicines in this group include avanafil Stendra, sildenafil Viagra, Revatio, and others, tadalafil Cialis and others, and vardenafil Levitra, Staxyn. Mass market pharmacies like CVS, Walmart, and Walgreens also offer discounts and coupons you can find online. When will Cialis be available to pharmacies. Check with your doctor right away if you have a sudden decrease in hearing or loss of hearing, which may be accompanied by dizziness and ringing in the ears. Research shows that Addyi changes the brain’s serotonin system and indirectly affects dopamine. Individual responses to our Male Enhancer Supplement vary.

Find Your Bezzy Community

Careful counseling along these lines might improve treatment compliance. Tell your doctor about all the medicines you take before you start taking ADDYI. BPH may cause problems with urination such as the need to urinate frequently or having to urinate more often at night. This service operates in the United Kingdom only. Your first look at the final episode of Gavin and Stacey. Yes, after an online consultation with one of our doctors or nurse practitioners, you can get the pills mailed to you from the Lemonaid Pharmacy in discreet plain packaging with FREE fast delivery. There aren’t any known interactions between Viagra and Adderall XR. All products displayed on Tata 1mg are procured from verified and licensed pharmacies. Premature ejaculation PS occurs when ejaculate leaves the penis too soon during sex. ED can occur if you have certain problems that affect your body’s ability to have an erection. The overall safety results from this study were generally consistent with the known safety profile of tadalafil and with adverse events AEs expected in a paediatric DMD population receiving corticosteroids. It was approved by the Food and Drug Administration in June 2023. Perhaps even more dangerous than the counterfeit PDE 5i that is marketed as legitimate pharmaceuticals, however, are those marketed as “natural” supplements. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. Minor 1drospirenone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. It should remain active for 4 6 hours after ingestion. Tadalafil tablets are usually light yellow and capsule shaped. Daré, a pharmaceutical company, is in the process of seeking approval from the F. Who should not take ADDYI. How to do perfume layering – and 10 of the best body lotions to give this Christmas. Medicines and treatments. All value packs and bundles. National Library of Medicine. Get a little extra sleep. Keep in mind that ED is often caused by other medications you may be taking or an underlying health condition.

Dosage Forms And Strengths

So, your doctor can prescribe a drug however they think is best for your care. Tadalafil is >10,000 fold more potent for PDE5 than for PDE3, an enzyme found in the heart and blood vessels. Instead, the best way to dispose of your medication is through a medicine take back program. Obesity Reviews, 17: 970– 976. ED is a condition in which you can’t get or keep an erection. GIFT THE DIOR DREAMShop now. Keeping this cookie enabled helps us to improve our website. Crossing the Line: Recognizing Overindulgence Risks. See also erectile dysfunction FAQs page. Physicians should consider the potential cardiac risk of sexual activity in patients with pre existing cardiovascular disease. Several years ago, the observation that one of the adverse effects of SSRIs when used to treat depression and other psychological disorders, ie, anorgasmia or delayed ejaculation, suggested SSRIs as a possible pharmacotherapy for PE. If you buy Cialis from a non Australian source such as overseas from India or Southeast Asia it can be potentially dangerous. To measure improvement of BPH, researchers used a scale called the International Prostate Symptom Score IPSS. Electrical beauty savings. The school system is broken’: Why more parents are home educating their children. Note: For more information about the potential negative effects of Cialis, see the “Cialis side effects” section above. Separately, the Tier 1 icon means that an online pharmacy accredited by PharmacyChecker only fills prescription orders through their own pharmacy or dispensing pharmacy partners in Australia, Canada, Israel, New Zealand, United Kingdom, or the U. People can save money on sildenafil 100 mg by comparing sildenafil prices at Canadian and international online pharmacies with discount prices available at U. Patients who get back pain and muscle aches usually get them 12 to 24 hours after taking Cialis and these usually go away by themselves within 48 hours. Hydroxyzine and vardenafil both increase QTc interval. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Following 16 weeks of tadalafil treatment in adult PAH patients, the model predicted increase in 6 min walk distance is more than 30 meters for the 20 and 40 mg doses, irrespective of bosentan use. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Upping your dose of Cialis increases your chances of serious side effects and damage, including. While you take Cialis, it’s best to avoid eating grapefruit and drinking grapefruit juice. Tell your healthcare provider about all of your health conditions and any prescription or over the counter OTC medicines, vitamins/minerals, herbal products, and other supplements you are using. If severe or persistent, consult a medical professional. View Pharmacy Profile. Dose reduction may be needed for coadministered drugs that are predominantly metabolized by CYP3A. PDE5 inhibitors, including VIAGRA, may potentiate the hypotensive effects of GC stimulators.

ATC code:

Read and follow these instructions carefully before you start using sildenafil and each time you get a refill of your medicine. Our experts create high quality content about medicines, diseases, lab investigations, Over The Counter OTC health products, Ayurvedic herbs/ingredients, and alternative remedies. This may temporarily increase the size of your penis, until the erection goes away. Female orgasms are often. Adjusting dosages might be necessary under medical guidance. Now, we’ll delve into how or if these ingredients can potentially provide the benefits suggested by Promescent. Most common fast acting PDE5 drug that lasts in your system for up to 18 hours. This article describes the FDA approved medications, including how they work and the possible side effects. Following at least 14 consecutive days of doxazosin, VIAGRA 50 mg or matching placebo was administered simultaneously with doxazosin 4 mg 17 subjects or with doxazosin 8 mg 3 subjects. WHAT IMPORTANT INFORMATION SHOULD YOU KNOW ABOUT LEVITRA. But instead of going to the pharmacy in person, or taking their chances buying from an online pharmacy of unknown repute, men will be able to buy Viagra from the maker of the drug itself and have it shipped to their homes. Patients not achieving >60% penile rigidity by 70 min postdose as measured by a RigiScan® monitoring device were assigned an onset time of 70 min. In 1998, the Food and Drug Administration FDA approved Viagra, the first medication to treat ED. Does Health Insurance Cover ED Meds. Respiratory syncytial virus service. Some side effects may occur that usually do not need medical attention. Ginseng is thought to boost the production of nitric oxide. Wisp, however, does something for OMG. For erectile dysfunction, it increases blood flow to the penis when aroused. Diary data indicated that on VIAGRA, 48% of intercourse attempts were successful versus 12% on placebo. Each film coated tablet contains 100 mg Sildenafil as sildenafil citrate. Pfizer’s new Viagra home delivery online offering can be accessed through Viagra. You should take Cialis exactly as it’s prescribed for you. J Int Soc Sports Nutr.

Searching

In two separate studies, approximately 780 females experiencing a variety of sexual dysfunctions were randomized to receive sildenafil or a matching placebo. It is allowed only in licensed pharmacies to be dispensed with legal prescriptions and even drug stores are not allowed to hold these drugs. These substances are malleable at normal ambient temperatures, a melting point above approximately 45 C, relatively low viscosity when melted, insoluble in water, and hydrophobic. Female libido pill gets US approval. Overdose symptoms are similar to the typical side effects of Cialis. However, if you have any concerns about the safety of the medicine, possible drug interactions, or how the medication may affect you, it’s best to speak to a doctor. Physicians should advise patients to stop use of all phosphodiesterase type 5 PDE5 inhibitors, including LEVITRA, and seek medical attention in the event of sudden loss of vision in one or both eyes. 6 The benefits and adverse effects of dapoxetine treatment should be reviewed after four weeks or six doses. A review published three years after Viagra’s FDA approval for treating erectile dysfunction ED summarizes the worldwide responses to treatment. The main difference between Kamagra and other ED medications is that the other treatments mentioned are licensed, regulated and approved. Skin care for aging skin: Minimizing age spots, wrinkles, and undereye bags. Tadalafil should not be taken while you are using certain other medicines. The most common side effects of tadalafil include. Yes, alprostadil is a medication that comes in topical form. Powered by DIGITAL SHOWROOM APP. Men should not take Cialis without further assessment from their GP if any of the following apply. Avoid or Use Alternate Drug. While labels on over the counter OTC erection pills and products may hint they are just like Viagra sildenafil or another erectile dysfunction ED drug, their benefits remain largely unproven. That means it will take a bit longer to work. It was first approved in 2003. In dogs given tadalafil daily for 6 to 12 months at doses of 25 mg/kg/day resulting in at least a 3 fold greater exposure than seen in humans given a single 20 mg dose and above, there was regression of the seminiferous tubular epithelium that resulted in a decrease in spermatogenesis in some dogs. The Papers: Chinese spy suspect named and ‘stark choice’ for Starmer. Cialis and vardenafil have different FDA approved uses, but they’re both used to treat ED. However, little data indicates that it is safe or effective for females, and the FDA has not approved it for this use. Price match guaranteePrescription issued online small prescription fee per order. ED affects about 150 million men worldwide, and the number of subjects who suffer from ED is expected to double by 2025 as the result of improved life expectancy and the age related nature of ED. They start from around $20, and individuals can choose between 6 and 9 mg pills. Megalis D 10/30 Tablet 4’s.

Priligy Tablets 30mg and 60mg reviews

Throw away any remaining liquid 60 days after it has been mixed for you by a pharmacist or healthcare professional. Share sensitive information only on official, secure websites. Talk with your doctor if you have questions or concerns about your current dosage. As they progress through college. Below is the list of medicines, which have the same composition, strength and form as Kamagra Gold 100 MG Tablet , and hence can be used as its substitute. Visit experience days. Interaction with Lab Test. Christmas and New Year. At 3 grams or more per day, you may experience. It is not known if or how tadalafil could affect pregnancy or harm an unborn baby. Your healthcare provider may recommend limiting or avoiding grapefruit while taking sildenafil. Stay on top of latest health news from Harvard Medical School. Use of the term “female” in this article refers to sex assigned at birth. Side effects, like facial flushing, headache or upset stomach, typically prove mild. If you take sildenafil for pulmonary arterial hypertension, do not take Viagra® or other PDE5 inhibitors, including tadalafil Cialis® or vardenafil Levitra®. Nappies, wipes and bathing. In patients with erectile dysfunction, 60% 70% of patients will see a positive outcome from the use of PDE5 inhibitor medicines like Sildenafil. If you’re having trouble opening medication bottles, ask your pharmacist about putting tadalafil tablets in an easy open container. Oral medicine for ED also might not be safe or work well if you have. It’s for women who are not happy with their low sex drive. This is consistent with ritonavir’s marked effects on a broad range of P450 substrates. Personalised photo gifts. VIAGRA sildenafil citrate is supplied as blue, film coated, rounded diamond shaped tablets containing sildenafil citrate equivalent to the nominally indicated amount of sildenafil and debossed on the obverse and reverse sides as follows. A decrease in − 2LL of 10. Read on for more information on the different dosages of Viagra, and which one is right for you. Because Kamagra is unlicensed, taking it could be dangerous for your health.

Salt Composition: Sildenafil + Dapoxetine

IPSS is a questionnaire that was given to people to determine whether their BPH symptoms improved. 4 mmHg when alcohol was administered alone. Sales of PalPal by Hanmi Pharmaceuticals totalled ₩22 billion or about 86% the market share of Viagra that year. As per the Brass process endorsed by regulatory authorities, an evidence based Brass value tree was developed, which identified the incremental benefits and risks that should be considered above the safety and efficacy evidence required for prescription medicines. 48/5 in 2960 product reviews. You can use it as needed up to three times per week. Federal government websites often end in. This medication is not usually used in women. 5 mg when used concomitantly with certain CYP3A4 inhibitors. Visit hair styling tools. ” Viagra comes as a tablet that you swallow. Cialis is approved to treat erectile dysfunction ED, symptoms of benign prostatic hyperplasia BPH, or both of these conditions. You should store sildenafil in its original packaging, below 30°C and away from sunlight and moisture. Prostate cancer: Short course radiation as effective as longer term treatments. Risks include undisclosed ingredients and harmful side effects. Tell your doctor if you are taking, have recently taken, or might take any other medicines. Hims and Hers has strict sourcing guidelines to ensure our content is accurate and current. Sildenafil is also available in an injectable form that is usually given by a healthcare provider in a hospital or clinic. There is a problem with information submitted for this request. 100 Community Place, Crownsville, MD 21032. “Addyi is a great addition to our relationship. While you look for natural options to increase sexual desire, it’s important to be aware of supplements that may do more harm than good. If you are trying to access this site from the United States and believe you have received this message in error, please reach out to and let us know. You do not have to take Cialis at any specific time before sexual activity when it’s prescribed in this way. For more about Tier 1 international pharmacies click here. We’re now transferring you to the website of our trusted partner, Chemist Direct, to complete your purchase. Cialis tadalafil is a prescription tablet used for erectile dysfunction and benign prostatic hyperplasia. At first, he was hesitant, but after consulting his doctor, he decided to give it a try. The pharmacokinetic profile of dapoxetine suggests that it is a good candidate for on demand treatment of PE.

Manufacturer: Centurion Remedies

Systematic Review of l Arginine for the Treatment of Hypoactive Sexual Desire Disorder and Related Conditions in Women. I will be a loyal customer for a long t. Do not take VIAGRA if you. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital. Kava traces its heritage to the South Pacific, where its root has long been used to make an intoxicating ceremonial beverage, similar to the role alcohol plays in the West. For information about Tier 1 international pharmacies click here. Advertising revenue supports our not for profit mission. Sildenafil tablets can interact with other medicines. If you’re taking Cialis and use antacids to treat heartburn, the antacids may decrease the level of Cialis that your body absorbs. Tím zajistíte, že přípravek používáte správně a efektivně. There aren’t any studies to show if it’s safe to take Viagra with illegal drugs, such as cocaine. Before you take ADDYI, tell your doctor about all of your medical conditions, including if you. View Pharmacy Profile. VIAGRA is rapidly absorbed after oral administration, with a mean absolute bioavailability of 41% range 25–63%. Are you nuts for nuts. Men over 75 years old are more likely to have it, but young men can experience ED too. Visit fragrance offers. Article Google Scholar.

Useful Links

For pregnant women: Research in animals has not shown a risk to the fetus when the mother takes the drug. This may reduce the problems with the flow of urine which are symptoms of benign prostatic hyperplasia. It can also cause airway inflammation and should not be used in people with chronic obstructive pulmonary disease COPD or poorly controlled asthma. Create profiles for personalised advertising. All Viagra is the same — powered by the same active ingredient, Sildenafil. It works by increasing the production of aqueous humour fluid in the eye and reducing eye pressure. Regarding how sildenafil and tadalafil work, they are very similar in that they are both PDE 5 inhibitors. The drug comes in low dose versions that can be taken daily. Those looking for an efficient therapy for ED might find discreet and prompt relief with its gentle formulation. A: Super Tadarise can be effective for many men with both ED and PE, but its effectiveness may vary from person to person. Pulmonary arterial hypertension is a form of high blood pressure that impacts the arteries in the lungs and the heart. The generic form has the same use, dosage, safety, and effectiveness as the brand name drug. Viagra is a prescription drug used to treat erectile dysfunction. After 50, the drug can be used without concern.